Overall, SSDs require very little maintenance. Fragmentation doesn't slow them down, though it wouldn't hurt to run defrag once a month. They can withstand a "drop to the floor off of the desk" much better than a standard hard drive (though we don't recommend testing this statement). Overheating does not seem to be a problem either.

We recommend that you keep an eye on available free space. Since SSDs are smaller than conventional drives, they can quickly become full.

We would also recommend a disk check once a month. Hard drive errors and broken permissions can destabilize SSDs over time and create disk errors, and loss of data.

In Windows, click Start, Computer, then right-click the disk, click Properties, Tools, and Check Now. Check the box that says "Automatically Fix Errors" and click start. If this is not a boot drive, check disk will start immediately. If it is a boot drive, check disk will start the next time you reboot your computer. The next computer startup might take several minutes longer than normal whilst running check disk. Errors are fixed automatically. However, if you receive unrecoverable errors, you might need to replace the drive.

With MACs (Apple), to run a disk check, go to the Utilities folder and find the Disk Utility program. Run Verify Disk from the First Aid tab. If errors are found, you can run the repair tool. As for Disk Permissions, you don’t really need to bother checking it. The crew at Apple's Genius Bar doesn’t. Go ahead and click "repair disk permissions."

SSDs will wear out over time, just like any other hard drive. Make sure you have a good backup system.